Our Top Berberine Supplements of 2025

See the benefits, what to look for and what to avoid with our expert comparison.

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What Is Berberine?

Berberine has been used medicinally for over 3000 years due to its robust health and heart benefits. As a bioactive compound found in plants, this powerful ingredient has been shown to positively impact blood sugar levels, blood pressure, weight loss and heart health.

A good quality Berberine supplement could greatly help with promoting a healthier heart, weight loss and may be beneficial for those with diabetes. However, not all Berberine supplements are equal and choosing the wrong kind can be an ineffective, costly mistake.

We’ve listed below the benefits, what to look for and compared 5 leading products

Benefits of High Quality Berberine

Berberine Supplements can be a very effective and inexpensive way to boost your heart health. By choosing the right supplement, you may see an improvement from just 3-4 weeks.

  • Balances Blood Sugar Levels

  • Boosts Heart Health

  • Lowers Glucose Levels

  • Helps Balance Blood Pressure

  • Supports Healthy Weight Loss

  • Supports Healthy Cholesterol

What To Look For?

Berberine Supplements are NOT all the same. It’s important to choose quality, proven formulas from trusted brands to see real benefits.

  • At Least 650mg of Berberine Per Serving Choose a supplement that includes at least 650mg, with 650mg being the optimal dosage of Berberine. This dosage amount has been cited in multiple studies.
  • UK Made It is important to look for a product which is manufactured in the UK. This helps to ensure that the product ingredients are accurate and follow good manufacturing practices based on UK regulations.
  • Money-Back Guarantee It is important to buy from brands that stand behind their product. Without a guarantee, you could lose your money and end up with an ineffective product. It is recommended to look for brands that offer a 30-60 day money back guarantee.

What Should I Avoid?

  • Poor Formulations & Doses It is recommended to stay away from products which do not contain pure Berberine. While some supplements may include a complex of ingredients, it is best to look for pure Berberine supplements that come from natural sources such as Berberis Astrata.
  • Artificial Reviews Watch out for product listings on Amazon and other marketplaces with fake reviews. When it comes to supplements, you are safer buying directly from trusted brands who are based in the UK. Buying from marketplaces or middle men companies gives you no guarantee when things go wrong.

1. Berberine [ 1 ]

by Bettervits

Sponsored This is a sponsored recommendation by our preferred partner.

A+

OVERALL GRADE

TOTAL RANKING

  • Ingredient Safety
    9.9AVG. 9.9/10
  • Projected Efectiveness
    9.8AVG. 9.8/10
  • Value
    9.7AVG. 9.7/10
  • Return Policy
    9.5AVG. 9.5/10
  • Customer Satisfaction
    9.6AVG. 9.6/10

Pros

  • 750mg of Pure Berberine
  • Sourced from “Berberis Astrata”
  • Vegan Friendly
  • Free Shipping
  • 60 Day Money Back Guarantee

Cons

  • Only Available Online Only Available Online
  • Sometimes Out of Stock

The Bottom Line

Out of all the Berberine supplements we have reviewed in-house - Bettervits came out on top in almost every benchmark.

Firstly, this formula contains a potent 750mg serving of Berberine, which is one of the highest in the UK market. This is also the clinically studied dose which has shown material health benefits.

Most importantly, they use purely sourced Berberine from “Berberis Astrata”, a type of plant which contains Berberine.

In addition, Bettervits has become one of the biggest names when it comes nutrition in the UK. Their products are made in the UK and are backed by a 60 day money back guarantee, so readers can be assured of their quality and try them risk free.

* Results and rankings are based on subjective opinion and do not necessarily reflect typical results from the use of these products. Please visit product website for more information.
We found one coupon code for this product: PRO10 for 10% off
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2. Berberine Sulfate

by Solaray

B+

OVERALL GRADE

TOTAL RANKING

  • Ingredient Safety
    9.2AVG. 9.2/10
  • Projected Efectiveness
    9.0AVG. 9.0/10
  • Value
    9.1AVG. 9.1/10
  • Return Policy
    9.5AVG. 9.5/10
  • Customer Satisfaction
    8.8AVG. 8.8/10

Pros

  • Sourced From Berberis Astrata
  • UK Made
  • Includes Boswellia
  • Vegan Friendly

Cons

  • Low 500mg Dosage
  • Includes GelatineOnly 250mg of Berberine HCL
  • No Money Back Guarantee

The Bottom Line

This Berberine supplement by Solaray is a decent quality product, but does have some shortcomings.

While the dosage is reasonable at 500mg, just short of the 650mg recommended dosage, it only contains 250mg of Berberine HCL from Berberis Astrata.

This product is made in the UK which is a plus, but they do not offer any money back guarantee which makes it a bit riskier if you do not see the desired improvement.

* Results and rankings are based on subjective opinion and do not necessarily reflect typical results from the use of these products. Please visit product website for more information.
We found one coupon code for this product: PRO10 for 10% off
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3. Berberine 500

by Freak Athletics

C

OVERALL GRADE

TOTAL RANKING

  • Ingredient Safety
    8.7AVG. 8.7/10
  • Projected Efectiveness
    89AVG. 8.9/10
  • Value
    9.0AVG. 9.0/10
  • Return Policy
    8.2AVG. 8.2/10
  • Customer Satisfaction
    8.6AVG. 8.6/10

Pros

  • Sourced From Berberis Astrata
  • Vegan Friendly

Cons

  • Low 250mg Dose of Berberine
  • Includes Filler Ingredients
  • No Money Back Guarantee
  • Manufactured in Lithuania

The Bottom Line

This Berberine product sources its Berberine from Berberis Astrata, which is a pure form. However, it contains a much less than the recommended dosage, with just 250mg of Berberine. In addition, it claims to have 500mg, however misleadingly 250mg of this is in fact other ingredients.

In addition, their product is manufactured outside of the UK, which makes it harder to verify the quality and accuracy of the ingredient claims.

The company behind is UK based company Freak Athletics, however they do not currently offer any money back guarantee.

* Results and rankings are based on subjective opinion and do not necessarily reflect typical results from the use of these products. Please visit product website for more information.
We found one coupon code for this product: PRO10 for 10% off
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4. Berberine

by Supplemented

D

OVERALL GRADE

TOTAL RANKING

  • Ingredient Safety
    8.5AVG. 8.5/10
  • Projected Efectiveness
    8.0AVG. 8.0/10
  • Value
    8.1AVG. 8.1/10
  • Return Policy
    8.0AVG. 8.0/10
  • Customer Satisfaction
    8.4AVG. 8.4/10

Pros

  • 500mg Berberine
  • Made in UK

Cons

  • No Mention of Berberine Source
  • Uses Bovine Gelatin Capsule Shell
  • No Money Back Guarantee

The Bottom Line

Supplemented’s Berberine product is a reasonable quality product. It contains a good dose of 500mg, however this does fall slightly short of the 650mg+ recommended dose.

This product is manufactured in the UK, which improves accuracy and trust when it comes to supplements. However, the source of the Berberine ingredient used is not clear or specified. It is important to ensure a natural and pure source when looking for Berberine.

Overall, this product is reasonable but we have ranked it down due to the lower dosage, the lack of transparency of the source of Berberine and the lack of a money back guarantee.

* Results and rankings are based on subjective opinion and do not necessarily reflect typical results from the use of these products. Please visit product website for more information.
We found one coupon code for this product: PRO10 for 10% off
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5. Berberine

by Ambrosial

D-

OVERALL GRADE

TOTAL RANKING

  • Ingredient Safety
    8.5AVG. 8.5/10
  • Projected Efectiveness
    7.6AVG. 7.6/10
  • Value
    7.3AVG. 7.3/10
  • Return Policy
    8.1AVG. 8.1/10
  • Customer Satisfaction
    8.2AVG. 8.2/10

Pros

  • 500mg of Berberine
  • Vegan Friendly

Cons

  • Low Potency of 500mg
  • Made in India
  • Does Not Mention Source of Berberine
  • No Money Back Guarantee

The Bottom Line

Ambrosial’s Berberine product comes in last due to a few cons. Firstly, it is made in India and therefore may not follow UK manufacturing best practices. With little manufacturing oversight, there is a risk of having inaccurate ingredients or counterfeit products.

In addition, while it contains a reasonable dose of 500mg, slightly below the recommended 650mg, it does not specify where the Berberine is sourced from.

Lastly, the company does not offer a money back guarantee, which could mean customers may be out of pocket should they not see the desired effect.

* Results and rankings are based on subjective opinion and do not necessarily reflect typical results from the use of these products. Please visit product website for more information.
We found one coupon code for this product: PRO10 for 10% off
LEARN MORE

2025's Top Berberine Supplement

We analysed the most popular Berberine Supplements on the market in the UK. With a strict review process, encompassing formula analysis, customer reviews, value for money and overall buying experience, we have chosen Bettervits Berberine as #1

We believe they offer the best combination of thorough research, high quality ingredients and quality manufacturing. Not just that, they are a trusted brand with a 60 day money back guarantee which means no risk for our readers. 60 Day Return Policy

MADE
IN THE UK

FREE
SHIPPING

MONEY-BACK
Guarantee

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Disclosure

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We strive to ensure that comparisons are made on the basis of factual information such as ingredients, quantity of ingredients, real customer testimonials, manufacturing location, return policies and other pertinent information to evaluate a product.

The information contained within this site is not intended as a substitute for professional medical advice. If you have, expect to have, or suspect you may have any medical condition, you are urged to consult with a health care provider. These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any diseases or medical conditions.

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